Sitravatinib (MGCD516, Mirati Therapeutics, San Diego, California, USA) binds and blocks the activity of several kinases beyond c-MET, including AXL, MERTK, VEGFR1/2/3, DDR2, and members of the tropomyosin-related kinases (TRK), platelet-derived growth factor receptor (PDGFR), and ephrin (Eph) families, among others
Wiley, London Willekens H, Van Camp W, Van Montagu M, Inze D, Langebartels C, Sandermann H Jr (1994) Ozone, sulfur dioxide, and ultraviolet B have similar effects on mRNA accumulation of antioxidant genes in Nicotiana plumbaginifolia L
Pharmacotherapy Evolution in Alzheimers Disease: Current Framework and Relevant Directions
With precision-controlled dosage, auto-injectors help patients achieve desired outcomes while reducing the potential for side effects associated with improper injection techniques
Under optimal conditions, the body can produce this important peptide itself
Pulm Med